Multi Frequency- Harmonic Motion Imaging (MF-HMI) for Breast Cancer Imaging

Harmonic motion imaging (HMI) is an acoustic radiation force (ARF)- based method to interrogate mechanical properties like stiffness. To interrogate mechanical properties, HMI uses oscillatory ARF at a particular frequency (generally 25-100 Hz) and then, estimates the ARF-induced motion to infer stiffness of tissues. Recently, we proposed Multi frequency-HMI (MF-HMI) to collect the motion data from 100-1000 Hz in a single acquisition. The objective of this project is to validate and investigate MF-HMI for breast cancer imaging. The students will make new tissue-mimicking phantom, perform experiments on the phantoms and 4T1 breast cancer mouse tumor, and process the collected data in Matlab. More information here.