The Losonczy Lab is currently accepting applications for Undergraduate Research Intern positions. The lab uses cutting edge two-photon laser scanning imaging to measure neuronal activity in head-fixed, awake mice running on a treadmill and studies place cell representation and formation. Student interns will be working with postdoctoral scientist Dr. Adrian Negrean. Dr. Negrean’s project involves two-photon imaging of dendritic membrane potential and synaptic activity using voltage and glutamate sensors in hippocampal CA1 area pyramidal cells of mice running on a treadmill. All students with a strong background or interest in neuroscience, optics, mechanical design, computer science (Python programming), molecular biology and physics are encouraged to apply. Previous laboratory experience is encouraged, but not required. Applications will be accepted on a rolling basis, but please apply at your earliest convenience, as positions may quickly be filled. This is a great opportunity for any students looking for publication opportunities.
Train head-fixed mice to run on custom-made treadmills for non-operant tasks and imaging
Perform surgical procedures (cannula implants) to provide a viable window for electroporation and imaging
Reconstruct the 3D morphologies of neurons and contribute to data segmentation and analysis
Stain tissue samples with immunofluorescent markers for confocal imaging
Stereotactic viral injections to express fluorescent proteins in the brain
Mechanical/optical design of instrumentation using Autodesk Inventor
Organized and responsible, able to keep clear training, surgical, and experimental records
Previous laboratory experience is encouraged, but not required
Can work closely with the research team to maximize productivity
If you are interested in this position, please apply at the following link: https://forms.gle/RXPuFb3JvHEdb3BD9. Competitive candidates will be contacted for a laboratory tour and/or an interview with Dr. Adrian Negrean shortly. More information on the laboratory can be found at: http://www.losonczylab.org/. Images from the project have also been attached below.