Losonczy Lab (Zuckerman Institute) - Undergraduate Interns

The Losonczy Lab is currently accepting applications for Undergraduate Research Intern positions. The lab uses cutting edge two-photon laser scanning imaging to measure neuronal activity in head-fixed, awake mice running on a treadmill and studies place cell representation and formation. Student interns will be working with postdoctoral scientist Dr. Adrian Negrean. Dr. Negrean’s project involves two-photon imaging of dendritic membrane potential and synaptic activity using voltage and glutamate sensors in hippocampal CA1 area pyramidal cells of mice running on a treadmill. All students with a strong background or interest in neuroscience, optics, mechanical design, computer science (Python programming), molecular biology and physics are encouraged to apply. Previous laboratory experience is encouraged, but not required. Applications will be accepted on a rolling basis, but please apply at your earliest convenience, as positions may quickly be filled. This is a great opportunity for any students looking for publication opportunities. 


Job Description

  • Train head-fixed mice to run on custom-made treadmills for non-operant tasks and imaging
  • Perform surgical procedures (cannula implants) to provide a viable window for electroporation and imaging
  • Reconstruct the 3D morphologies of neurons and contribute to data segmentation and analysis
  • Stain tissue samples with immunofluorescent markers for confocal imaging
  • Stereotactic viral injections to express fluorescent proteins in the brain
  • Mechanical/optical design of instrumentation using Autodesk Inventor
  • Molecular cloning of plasmids
  • Programming and analysis of data

Ideal Candidate

  • Strong background and/or interest in biology, neuroscience, computer science (Python programming), and/or physics
  • Able to commit 8 to 12 hours per week
  • Organized and responsible, able to keep clear training, surgical, and experimental records
  • Previous laboratory experience is encouraged, but not required
  • Can work closely with the research team to maximize productivity

If you are interested in this position, please apply at the following link: https://forms.gle/RXPuFb3JvHEdb3BD9. Competitive candidates will be contacted for a laboratory tour and/or an interview with Dr. Adrian Negrean shortly. More information on the laboratory can be found at: http://www.losonczylab.org/. Images from the project have also been attached below.