Effects of repetitive mild blast-induced traumatic brain injury on hippocampal networks

Exposure to shock waves in military training has been the topic of growing concern that repeated exposure may be capable of inflicting neurocognitive deficits. In vitro experiments using organotypic hippocampal slice cultures have indicated repetitive mild blast-induced traumatic brain injuries lead to deficits in long-term potentiation, a cellular correlate to learning and memory. The lab aims to further utilize electrophysiological recordings to elucidate hippocampal network change using various network analysis methods.