Developing an iPSCs model of Spinal Muscular Atrophy using CRISPRi
We are sorry, this position has been filled.
The students will work on a project aim to model Spinal Muscular Atrophy (SMA) using human engineered tissues. The work will involve the use of human induced pluripotent stem cells, generation of plasmids and transgenic lines, motoneuron and muscle differentiations, microfabrication, RT-PCR, western blot and immunohistochemistry and confocal imaging.
Lab: Laboratory for Stem Cells and Tissue Engineering