Articular cartilage delamination wear and a novel treatment strategy to delay osteoarthritis progression

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Osteoarthritis is a degenerative disease of articular cartilage affecting more than 27 million Americans annually. The student would be working on one of the projects aimed atdeveloping a treatment to delay osteoarthritis progression and prevent the need for joint replacement surgery. The student would be working with PhD students to understand the mechanism of early articular cartilage stress-mediated damage and in the design of a new laser-based treatment option that could be introduced in earlier stages of OA. He would assist in in vitro experimental work: harvesting cartilage tissue, laser treatment, mechanical & biochemical testing of samples, analysis of data using MATLAB and preparing a manuscript. Apart from data acquisition and analysis, the student would help with computational modeling as well when required. The research responsibilities also include assisting with the preparation of experimental methodology and assisting in the preparation of an NIH grant proposal.

Lab: Musculoskeletal Biomechanics Lab

Direct Supervisor: Krista Durney

Position Dates: 6/1/2018 - 8/30/2018

Hours per Week: 40

Paid Position: Yes

Credit: No

Eligibility: Master's; SEAS only

Gerard Ateshian: ateshian@columbia.edu, Mudd 244, x48602